In his fourteen seasons, Renfro intercepted 52 passes, returning them for 626 yards and 3 touchdowns. He also returned 109 punts for 842 yards and 1 touchdown, 85 kickoffs for 2,246 yards and 2 touchdowns, along with
recording 13 fumble recoveries, which he returned for 44 yards. In the 1970 NFC title game, Renfro had a key interception that led to the Cowboys' game-winning touchdown over the San Francisco 49ers that helped them get to Super Bowl V, where they lost to the Baltimore Colts. He would later play in Super Bowls VI, X and XII, retiring after the final one, a Cowboys victory over the Denver Broncos.  Renfro was added to the Texas Stadium Ring of Honor in 1981, and was elected to the Pro Football Hall of Fame in 1996.