Don't miss this Private Tasting for 4, paired with charcuterie and cheese, at the Vintner's Collective, a multi-winery tasting room. It's housed in Napa's oldest commercial building, an 1875-built brewery and, later, a saloon and brothel. Here visitors can sample 18 wineries, some of which release wines in remarkably limited quantities (as few as 75 cases) and high prices (up to $75 a bottle). For novices, it's a chance to sample expensive, obscure wines.

French Laundry's Sommelier Keith Fergel says of his favorite winery stops, if he had to pick just one it would be Vintner's Collective. "It's all about great wine here."