The Women's Tennis Association (WTA) ranked her world No. 1 in singles on eight separate occasions between 2002 and 2017. Williams holds the most Grand Slam titles in singles, doubles, and mixed doubles combined among active players.

Her 39 major titles put her joint-third on the all-time list and second in the Open Era: 23 in singles, 14 in women's doubles, and two in mixed doubles. She has also won four Olympic gold medals, one in women's singles and three in women's doubles—an all-time record shared with her sister, Venus.

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