In three MLB seasons, Ramírez batted .259 with 12 home runs, 48 RBI, 38 runs, 17 doubles, three triples, and three stolen bases in 135 games.

After the 2000 season, Ramírez signed with the Tokyo Yakult Swallows (2001-2007) and was their cleanup hitter. He holds the Central League (Japan) record for most base hits in a single season (204) set in 2007.

In 2008, Ramírez led the Central League with 125 RBI while hitting .319 (6th in the league) with 45 home runs (2nd). He also hit two home runs in Game 2 of the Japan Series, including one in the bottom of the ninth to win Game 2.

At the end of the 2008 season, Ramírez won the Central League MVP Award to become the third Venezuelan player to be honored with the title in Japanese Baseball.