Step inside the historic Sise Inn, a 19th-century Queen Anne residence in Portsmouth, New Hampshire. Relax, unwind and let time slip away in one of the inn's 34 elegantly appointed guest rooms and suites. Whether you're here for a getaway, a business meeting or a special event, a stay at the Sise Inn will make your visit to Portsmouth and the seacoast of New Hampshire an unforgettable experience.  Includes Breakfast.